San Francisco 49ers news alert: The 49ers have made multiple picks in the 4th and 5th rounds of the 2025 NFL Draft, the 49ers have selected Jordan James, RB, Oregon, Jordan Watkins, WR, Ole Miss, and Marques Sigle, S, Kansas State. Chase Senior, host of the 49ers Report discusses what the latest 49ers draft picks mean for San Francisco and gives you his instant reaction to all three, in addition to the latest 49ers news, 49ers rumors, 49ers draft news, 49ers draft rumors and more. Chase Senior, host of the 49ers Report discusses what this 49ers draft pick means for San Francisco and gives you his instant reaction, in addition to the latest 49ers news, 49ers rumors, 49ers draft news, 49ers draft rumors and more. Catch the entire NFL Draft & 49ers news right here!

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San Francisco 49ers news during the 2025 NFL Draft. Chase Senior, after this 49ers draft pick as part of the 49ers 2025 draft class will discuss:
- Jordan James stats:
233 CAR, 1,267 Yards, 15 RUSH TDs
- Marques Sigle stats:
60 TKL, 3 INT, 3 PDs
- Jordan Watkins stats:
49 REC, 905 Yards, 9 TDs

San Francisco 49ers 2025 draft picks:
Round 1: 11th overall - Mykel Williams, EDGE, Georgia
Round 2: 43rd overall - Alfred Collins, DT, Texas
Round 3: 75th overall - Nick Martin, LB, Oklahoma State
Round 3: 100th overall (compensatory) - Upton Stout, CB, Western Kentucky
Round 4: 113th overall: CJ West, DT, Indiana
Round 4: 138th overall (compensatory): Jordan Watkins, WR, Ole Miss
Round 5: 147th overall (from NO via WAS): Jordan James, RB, Oregon
Round 5: 160th overall (via MIN): Marques Sigle, S, Kansas State
Round 7: 227th overall
Round 7: 249th overall (compensatory)
Round 7: 252nd overall (compensatory)

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49ers fans! Let us know what you're thinking in the comments
- Grade the 49ers draft so far! A, B, C, D or F?
- Who should the 49ers draft next?

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